Everyone on TikTok Is "Balancing Cortisol Levels" — Here's What That Means

In a society that sometimes seems obsessed with finding ways to biohack wellbeing, you've probably come across the cortisol conversation before. The hormone is often referenced on social media as something that needs to be "regulated" or balanced — and it's blamed for things like irregular sleep, bloating, and breakouts. But it's hard to parse out fact from fiction in today's health and wellness landscape.

In some cases, content creators — some qualified, many not — have recommended certain supplements, lifestyle changes, and nutritional choices in order to regulate cortisol and operate at optimal health. But balancing cortisol levels is a bit more complex than just a few changes to the way you eat and live. There are also certain conditions associated with high and low levels of cortisol that require specific treatment.

So before you try and regulate your cortisol levels, here's a break down of everything you need to know about the so-called "stress hormone" — including whether balancing your cortisol is necessary, or even possible.

Mary Gover, MD, AAHIVS, is an internist at Montefiore Einstein Advanced Care.

Akua Ampadu, MD, is a board-certified internal medicine physician, blogger at DrAkuaMD.com, and advocate for holistic wellness.

"Cortisol is one of several hormones produced by our adrenal glands, small glands found on top of either kidney," explains Akua Ampadu, MD, board-certified internal medicine physician and advisory board member for PS's Condition Center. "It is one of the hormones responsible for body functions like blood pressure and temperature regulation, inflammation and weight management."

The reason cortisol is often referred to as the stress hormone is because most people are familiar with it in the context of getting the body ready for fight or flight, says Mary Gover, MD, AAHIVS, internist at Montefiore Einstein Advanced Care. "It's job is to get the body ready for action," she says. "It increases our blood pressure and releases glucose into our blood stream for fuel."

"The body has a very elegant system to regulate hormones, including cortisol," Dr. Gover tells PS. Cortisol is released both on a natural rhythm (it's highest in the morning and decreases throughout the day) and in response to stimuli perceived by the brain as stressful.

In terms of how the hormone is actually released, Dr. Gover breaks it down: "The brain releases a hormone called ACTH, which acts on the adrenal gland and tells it to release cortisol," she tells PS. "When the brain senses that there is enough cortisol in the blood, it stops releasing ACTH. It's a feedback loop."

Increased cortisol levels can be caused by an increase in stress. "If your brain perceives stress frequently or continuously and is unable to manage that stress, then your body will release cortisol more frequently," Dr. Gover explains.

That said, wellness influencers can often blame symptoms of stress on "high cortisol," and the relationship isn't so straightforward. After all, stress and anxiety can cause issues like poor sleep, muscle tightness, and irritability — but whether those symptoms are all directly caused by high levels of cortisol is hard to say.

However, there are certain medical conditions associated with abnormally high levels of cortisol, particularly Cushing's Syndrome. The rare condition is often caused by a tumor in the pituitary gland, which helps regulate the production of cortisol by the adrenals, or long-term use of glucocorticoid medication. It's typically marked by a redistribution of weight in the face, abdomen and upper back, in addition to blood sugar elevation, blood pressure elevation, skin markings (that look like stretch marks), and bone weakness, Dr. Gover explains.

Again, it's hard to nail down what stress-related cortisol elevations might look like (since any stress symptom could theoretically be related to high cortisol). But here are some of the most common symptoms of clinically high cortisol levels, which are typically associated with Cushing's syndrome, according to Dr. Ampadu:

Extremely low cortisol levels are typically associated with Addison's disease, a condition that occurs when the adrenals don't produce enough of the hormone. It's characterized by symptoms such as lethargy, low appetite and low blood pressure, Dr. Ampadu explains.

If you have an underactive pituitary gland or a pituitary tumor, it can also limit ACTH production, per the Cleveland Clinic: "ACTH signals your adrenal glands to make cortisol, so limited ACTH results in limited cortisol production."

Low cortisol levels related to Addison's disease are typically associated with the following symptoms, per Dr. Ampadu:

Persistently elevated cortisol can lead to negative long-term health consequences on your blood pressure, immune system, cardiovascular health, and weight, per Dr. Gover. So "balancing your cortisol levels" — and more precisely, managing your stress levels — can be important.

"But balancing cortisol isn't done with medications or supplements or novel therapeutics," Dr. Gover tells PS. It is done by regulating your sleep, nutrition, and emotional stress. Physical activity can help as well. Below are some of Dr. Gover's specific recommendations:

Because there is not a pill or specific treatment "for cortisol," Dr. Gover doesn't recommend seeing your doctor about cortisol. She does however recommend seeing your PCP if you're experiencing high levels of stress that are impacting you emotionally (anxiety, worry) or physically (poor sleep, poor diet, lack of physical activity, unexpected weight changes). Your healthcare provider will be able to advise you on certain lifestyle changes or in the case of Addison's or Cushing's, specific treatment options.

Alexis Jones is the senior health and fitness editor at PS. Her passions and areas of expertise include women's health and fitness, mental health, racial and ethnic disparities in healthcare, and chronic conditions. Prior to joining PS, she was the senior editor at Health magazine. Her other bylines can be found at Women's Health, Prevention, Marie Claire, and more.